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Cyanine5,5 hydrazide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyanine5,5 hydrazide图片
规格:98%
分子量:669.73
包装与价格:
包装价格(元)
1mg电议
5mg电议
25mg电议
50mg电议
100mg电议

产品介绍
C40H46Cl2N4O
货号:ajcx28842
CAS:2280971-80-2(withoutanion)
分子式:C40H46Cl2N4O
分子量:669.73
溶解度:practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.