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Eleutheroside B1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eleutheroside B1图片
规格:98%
分子量:384.33
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Eleutheroside B1,香豆素化合物,具有广谱的抗人流感病毒 (influenza virus) 作用,其IC50 值为 64-125μg/ml。Eleutheroside B1 通过 POLR2A 和 N-糖基化介导其抗流感活性。Eleutheroside B1 抑制多种趋化因子基因和流感病毒核蛋白 (NP) 基因的 mRNA 表达,且具有较低的细胞毒性。具有抗病毒、抗炎活性。
货号:ajcx36750
CAS:16845-16-2
分子式:C17H20O10
分子量:384.33
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].

Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1].

[1]. Yan W, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.Int J Mol Med. 2018 Nov;42(5):2776-2792.