Promestriene 是一种合成的雌二醇二乙醚，是一种局部有效的雌激素。Promestriene 对阴道萎缩有有效的治疗作用，但吸收量小。
货号:ajcx16746
CAS:39219-28-8
分子式:C22H32O2
分子量：328.49
溶解度:DMSO: 20 mg/mL (60.88 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed [1][2].

[1]. Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51. [2]. Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98. [3]. AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.