L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP.
货号:ajcx18638
CAS:N/A
分子式:C29H50N2O3•HCl
分子量：511.2
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP . It inhibits the growth of MCF-7, MDA-MB-468, and SK-BR-3 breast cancer cells (ED50s = 4, 7, and 6 μM, respectively) through damage of cell organelle membranes, increasing ceramide concentration, and induction of apoptosis.