| 规格: | 98% |
| 分子量: | 537.7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
Background:
Des(benzylpyridyl) atazanavir is a major metabolite of the HIV-1 protease inhibitor atazanavir .1,2 It is formed from atazanavir by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6.2
|1. ter Heine, R., Hillebrand, M.J.X., Rosing, H., et al. Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor. Drug Metab. Dispos. 37(9), 1826-1840 (2009).|2. Li, F., Lu, J., Wang, L., et al. CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism. Drug Metab. Dispos. 39(3), 394-401 (2011).
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