您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > 13,14-dihydro Prostaglandin E1-d4
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
13,14-dihydro Prostaglandin E1-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
13,14-dihydro Prostaglandin E1-d4图片
规格:98%
分子量:360.5
包装与价格:
包装价格(元)
25ug电议
50ug电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx21090
CAS:N/A
分子式:C20H32D4O5
分子量:360.5
溶解度:DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

13,14-dihydro Prostaglandin E1-d4(13,14-dh PGE1-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh PGE1by GC-or LC-mass spectrometry. 13,14-dh PGE1is an inhibitor of ADP-induced platelet aggregation in human platelet-rich plasma and washed platelets with IC50values of 31 and 21 nM, respectively.113,14-dh PGE1is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1which has an IC50of 40 nM.2Also, 13,14-dh PGE1activates adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.3


1.Kobzar, G., Mardla, V., JÄrving, I., et al.Comparison of the inhibitory effect of E-prostaglandins in human and rabbit platelet-rich plasma and washed plateletsComparative Biochemistry and Physiology106(2)489-494(1993) 2.Kobzar, G., Mardla, V., JÄrving, I., et al.Antiaggregating potency of E-type prostaglandins in human and rabbit plateletsProceedings of the Estonian Academy of Sciences.Chemistry40179-180(1991) 3.Blair, I.A., Hensby, C.N., and MacDermot, J.Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationshipsBr. J. Pharmac.69(3)519-525(1980)