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C26 Sphingomyelin-d4(d18:1/26:0-d4)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C26 Sphingomyelin-d4(d18:1/26:0-d4)图片
规格:98%
分子量:847.3
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx21944
CAS:N/A
分子式:C49H95D4N2O6P
分子量:847.3
溶解度:
纯度:98%
存储:Store at -20°C
库存:现货

Background:

C26 Sphingomyelin-d4is intended for use as an internal standard for the quantification of C26 sphingomyelin by GC- or LC-MS. C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 Sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 Sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.]


1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicityAnal. Chem.86(12)5688-5696(2014) 2.Willmann, J., Mahlstedt, K., Leibfritz, D., et al.Characterization of sphingomyelins in lipid extracts using a HPLC-MS-offline-NMR methodAnal. Chem.79(11)4188-4191(2007) 3.Jenkins, R.W., Clarke, C.J., Lucas, J.T., Jr., et al.Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosisAm. J. Hematol.88(11)E265-E272(2013) 4.Li, X.M., Momsen, M.M., Brockman, H.L., et al.Sterol structure and sphingomyelin acyl chain length modulate lateral packing elasticity and detergent solubility in model membranesBiophys. J.85(6)3788-3801(2003)