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Progesterone-d9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Progesterone-d9图片
包装:1mg
规格:98%
市场价:2080元
分子量:323.5

产品介绍
An internal standard for the quantification of progesterone
货号:ajcx23304
CAS:15775-74-3
分子式:C21H21D9O2
分子量:323.5
溶解度:Acetonitrile: 1 mg/ml,Ethanol: 1 mg/ml,Methanol: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Progesterone-d9is intended for use as an internal standard for the quantification of progesterone by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones.1Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50value of 0.5 nM.2


1.Erickson, G.F.The ovary: Basic principles and concepts. A. PhysiologyEndocrinology and Metabolism3rd ed.973-1015(1995) 2.Pedram, B., van Oeveren, A., Mais, D.E., et al.A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinolineJ. Med. Chem.51(13)3696-3699(2008)