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Debutyldronedarone D6 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Debutyldronedarone D6 hydrochloride图片
包装:1mg
规格:98%
市场价:2227元
分子量:543.15

产品介绍
DebutyldronedaroneD6hydrochloride(SR35021D6hydrochloride)是Debutyldronedarone的氘代物。Debutyldronedarone是Dronedarone在人体中的主要循环活性代谢物(metabolite)。Debutyldronedarone的效力是Dronedarone的1/10到1/3。
货号:ajcx30474
CAS:1346598-70-6
分子式:C27H31D6ClN2O5S
分子量:543.15
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].


[1]. Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci [2]. Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.