Nilofabicin是一种 FabI 抑制剂。Nilofabicin 对金黄色葡萄球菌的 MIC(90) 为0.5 microg/ml，比利奈唑胺或万古霉素更有效。
货号:ajcx35036
CAS:934628-27-0
分子式:C19H20N2O2S
分子量：340.44
溶解度:DMSO : 100 mg/mL (293.74 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].

[1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591-2593.