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L-Aspartic acid-15N
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Aspartic acid-15N图片
规格:98%
分子量:134.1
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
L-Aspartic acid-15N 是一种 15N 标记的 L-Aspartic acid。L-Aspartic acid 是一种氨基酸,被证明是一种结肠特异性药物输送的前体药物。
货号:ajcx37232
CAS:3715-16-0
分子式:C4H715NO4
分子量:134.1
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

L-Aspartic acid-15N is the 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406.
[3]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11.