Podophyllotoxone 是从八角莲根中分离得到的，具有抗癌活性。Podophyllotoxone 能够抑制 tubulin 微管蛋白聚合。
货号:ajcx38136
CAS:477-49-6
分子式:C22H20O8
分子量：412.39
溶解度:DMSO : 100 mg/mL (242.49 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].

Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC50 values of 14.7 and 20.6 µM[1].

[1]. Juan Li , et al. Absolute Configuration of Podophyllotoxone and Its Inhibitory Activity Against Human Prostate Cancer Cells. Chin J Nat Med. 2015 Jan;13(1):59-64.