carbonyl-reactive dye
货号:ajcx11242
CAS:N/A
分子式:C38H44Cl2N4O
分子量：643.69
溶解度:≥ 64.4mg/mL in DMSO, ≥ 33.33 mg/mL in EtOH with ultrasonic
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cy3.5 hydrazide is a near infrared fluorophore that can react with various carbonyl groups in biomolecules which are generated after oxidative stress or deamination of proteins. In addition, aldehyde moieties can be produced by periodate oxidation of sugar residues of glycoproteins, such as antibodies that can then be oxidized by sodium periodate and labeled with Cy3.5 hydrazide to form Cy3. 5 labeled antibodies. For biomolecule labeling, the labeling regent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.