Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535). Lofepramine produces inhibition of liver tryptophan pyrollase activity in vitro. References: Feighner JP, Meridith CH, Dutt JE, Hendrickson GG. A double blind comparison of lofepramine, imipramine and placebo in patients with depression. Acta Psychiatr Scand. 1982 Aug;66(2):100-8. PubMed PMID: 6753500.

纯度：≥98%

CAS：23047-25-8