Tegatrabetan (BC2059) 是一种 β-Catenin 拮抗剂。Tegatrabetan 破坏 β-catenin 与转导素 β 样蛋白 1 (TBL1) 结合。
货号:ajcx16096
CAS:1227637-23-1
分子式:C28H36N4O6S2
分子量：588.74
溶解度:DMSO: 125 mg/mL (212.32 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1)[1].

[1]. Fiskus W, et al. Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells. Leukemia. 2015 Jun;29(6):1267-78.