Proscillaridin A 是强力的拓扑异构酶 I 和 II topoisomerase I/II 抑制剂，抑制拓扑异构酶 I 和 II 的 IC50 值分别为 30 nM 和 100 nM。
货号:ajcx16608
CAS:466-06-8
分子式:C30H42O8
分子量：530.65
溶解度:DMSO: 100 mg/mL (188.45 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Proscillaridin A is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively[1].

[1]. Bielawski K, et al. Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A.Biol Pharm Bull. 2006 Jul;29(7):1493-7.