您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Globotriaosylceramides(non-hydroxy)(porcine)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Globotriaosylceramides(non-hydroxy)(porcine)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Globotriaosylceramides(non-hydroxy)(porcine)图片
包装:500ug
规格:98%
市场价:5704元
分子量:1052.4

产品介绍
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
货号:ajcx18494
CAS:N/A
分子式:C54H101NO18 (for stearoyl)
分子量:1052.4
溶解度:Chloroform:Methanol (2:1): soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. Globotriaosylceramides act as natural resistance factors to HIV infection, interacting with HIV gp120 to prevent its interaction with chemokine co-receptors and subsequent fusion of HIV to host cell membranes. This product contains a mixture of non-hydroxy fatty acid-containing globotriaosylceramides isolated from porcine red blood cells (RBCs).