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NADP+(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NADP+(hydrate)图片
规格:98%
分子量:743.4
包装与价格:
包装价格(元)
50mg电议
100mg电议
500mg电议
1g电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx23052
CAS:N/A
分子式:C21H28N7O17P3.XH2O
分子量:743.4
溶解度:PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

NADP+is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions.1,2In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling.2,3For example, binding of NADP+to β-subunits of Kvchannels activates ion transport, whereas NADPH stabilizes channel inactivation.4NADP+is biosynthesized from NAD+by NAD kinase, with ATP as the phosphoryl donor.5


1.Jackson, J.B.A review of the binding-change mechanism for proton-translocating transhydrogenaseBiochimica et Biophysica Acta1817(10)1839-1846(2012) 2.Nakamura, M., Bhatnagar, A., and Sadoshima, J.Overview of pyridine nucleotides review seriesCirc. Res.111(5)604-610(2012) 3.Ziegler, M.A vital link between energy and signal transduction: Regulatory functions of NAD(P)FEBS Journal272(18)4561-4564(2014) 4.Kilfoil, P.J., Tipparaju, S.M., Barski, O.A., et al.Regulation of ion channels by pyridine nucleotidesCirc. Res.112(4)721-741(2013) 5.Shi, F., Li, Y., Li, Y., et al.Molecular properties, functions, and potential applications of NAD kinasesActa Biochim. Biophys. Sin. (Shanghai)41(5)352-361(2009)