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PtdIns-(1-arachidonoyl,2-arachidonoyl-d8)(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PtdIns-(1-arachidonoyl,2-arachidonoyl-d8)(ammonium salt)图片
规格:98%
分子量:932.2
包装与价格:
包装价格(元)
25ug电议
50ug电议
100ug电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx23362
CAS:N/A
分子式:C49H70D8O13P.NH4
分子量:932.2
溶解度:CHCl3:CH3OH:H2O (3:2:1): 10 mg/ml,PBS (pH 7.2): Freely soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

PtdIns-(1-arachidonoyl, 2-arachidonoyl-d8) is used as an internal standard for the quantification of PtdIns-(1-arachidonoyl, 2-arachidonoyl) by stable isotope dilution MS. The accuracy of the sample weight in this vial is between5% over and 2% under the amount shown on the vial. If better precision is required, the deuterated standard should be quantitated against a more precisely weighed unlabeled standard by constructing a standard curve of peak intensity ratios (deuteratedversusunlabeled). The phosphatidylinositols (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2PtdIns-(1-arachidonoyl, 2-arachidonoyl-d8) (sodium salt) is a synthetic analog of natural PtdIns featuring deuterated C20:4 fatty acids at thesn-2 position. This synthetic standard compound contains the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound.


1.Lapetina, E.G., Billah, M.M., and Cuatrecasas, P.The phosphatidylinositol cycle and the regulation of arachidonic acid productionNature292367-369(1981) 2.Pike, L.J., and Casey, L.Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domainsThe Journal of Biological Chemisty27126453-26456(1996)