| 规格: | 98% |
| 分子量: | 524.5 |
| 包装 | 价格(元) |
| 500ug | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
Background:
Mometasone furoate-d3is intended for use as an internal standard for the quantification of mometasone furoate by GC- or LC-MS. Mometasone furoate is a prodrug form of the synthetic glucocorticoid mometasone .1Intranasal administration of mometasone furoate (1 µg/nostril) reduces the frequency of sneezing and nasal rubbing in a rat model of histamine-induced allergic rhinitis.2Topical application of mometasone furoate reduces croton oil-induced ear edema in mice (ED50= 0.31 µg/ml).3Formulations containing mometasone furoate have been used in the treatment of allergic rhinitis, atopic dermatitis, and asthma.
1.Smith, C.L., and Kreutner, W.In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoidsArzneimittel-Forschung48(9)956-960(1998) 2.Altunta?, E.E., Do?an, O.T., SaraÇ, B., et al.The effects of mometasone furoate and strontium chloride in a rat model of allergic rhinitisEar Nose Throat J.97(1-2)E1-E7(2018) 3.Ogawa, M.Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in miceImmunopharmacol. Immunotoxicol.31(4)601-606(2009)
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