A bacterial metabolite
货号:ajcx24750
CAS:55812-46-9
分子式:C14H14N2O3
分子量：258.3
溶解度:
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pyrindolol is a bacterial metabolite that has been found inS. alboverticillatus.¹It inhibits neutral β-galactosidase by 50% under acidic, but not neutral, conditions when used at a concentration of 2 µg/ml. It is selective for β-galactosidase isolated from bovine liver over β-galactosidases isolated from human, bovine, pig, and rat tissues and sialidases isolated fromC. perfringens,Streptomyces, and the H3N2 strain of influenza virus (IC₅₀s = >250 µg/ml for all).^1,2

1.Aoyagi, T., Kumagai, M., Hazato, T., et al.Pyridindolol, a new β-galactosidase inhibitor produced by actinomycetesJ. Antibiot. (Tokyo)28(7)555-557(1975) 2.Kumagai, M., Aoyagi, T., and Umezawa, H.Inhibitory activity of pyridindolol on β-galactosidaseJ. Antibiot. (Tokyo)29(7)696-703(1976)