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Nitrofurantoin-13C3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nitrofurantoin-13C3图片
规格:98%
分子量:241.1
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
An internal standard for the quantification of nitrofurantoin
货号:ajcx24798
CAS:1217226-46-4
分子式:C5[13C]3H6N4O5
分子量:241.1
溶解度:DMSO: slightly soluble,Methanol: slightly soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as calculi and abscess formation, in a rat model ofP. vulgarisurinary tract infection.2Formulations containing nitrofurantoin have been used to treat urinary tract infections.


1.Rocha, H., Da Silva Teles, E., and Barros, M.Site of action of nitrofurantoin in experimental urinary tract infectionAppl. Microbiol.18(4)547-549(1969) 2.Hossack, D.J.N.Proteus vulgaris urinary tract infections in rats; treatment with nitrofuran derivativesBr. J. Pharmacol. Chemother.19(2)306-312(1962)