An aminoglycoside antibiotic
货号:ajcx24962
CAS:N/A
分子式:C21H41N5O11·XH2SO4 [XH2O]
分子量：539.6
溶解度:PBS (pH 7.2): 10 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Apramycin is an aminoglycoside antibiotic first isolated fromS. tenebrarius.¹It is active against a variety of Gram-positive and Gram-negative bacteria, including strains which produce aminoglycoside-modifying enzymes.²Apramycin inhibits protein synthesis in bacteria bothin vivoandin vitro.¹

1.Perzynski, S., Cannon, M., Cundliffe, E., et al.Effects of apramycin, a novel aminoglycoside antibiotic on bacterial protein synthesisEur. J. Biochem.99(3)623-628(1979) 2.Abe, Y., Nakagawa, S., Naito, T., et al.Aminoglycoside antibiotics. XIV. Synthesis and activity of 6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-and 5-O-(β-D-ribofuranosyl)apramycinsJ. Antibiot. (Tokyo)34(11)1434-1446(1981)