您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Tauro-α-muricholic Acid-d4(sodium salt)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tauro-α-muricholic Acid-d4(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tauro-α-muricholic Acid-d4(sodium salt)图片
规格:98%
分子量:541.7
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
An internal standard for the quantification of tauro-α-muricholic acid
货号:ajcx25004
CAS:N/A
分子式:C26H40D4NO7S·Na
分子量:541.7
溶解度:DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Tauro-α-muricholic acid-d4(TαMCA-d4) is intended for use as an internal standard for the quantification of TαMCA by GC- or LC-MS. TαMCA is an antagonist of the farnesoid X receptor (FXR; IC50= 28 µM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid .1TαMCA is common in rodents but has also been found in small amounts in human serum.2


1.Sayin, S.I., WahlstrÖm, A., Felin, J., et al.Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonistCell Metab.17(2)225-235(2013) 2.GarcÍa-CaÑaveras, J.C., Donato, M.T., Castell, J.V., et al.Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated methodJ. Lipid Res.53(10)2231-2241(2012)