A thyroid hormone derivative
货号:ajcx26526
CAS:26041-51-0
分子式:C17H13I4NO5
分子量：818.9
溶解度:DMF: 14 mg/mL,DMSO: 25 mg/mL,Ethanol: 20 mg/mL,PBS (pH 7.2): 0.2 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

N-Acetyl-L-thyroxine is an acetylated derivative of L-thyroxine .¹It only weakly binds to thyroxine-binding globulin (TBG) in isolated human serum with a relative binding affinity of 25 compared with L-thyroxine. N-Acetyl-L-thyroxine is also a potential impurity in commercial preparations of L-thyroxine.²

1.Snyder, S.M., Cavalieri, R.R., Goldfine, I.D., et al.Binding of thyroid hormones and their analogues to thyroxine-binding globulin in human serumJ. Biol. Chem.251(21)6489-6494(1976) 2.Panmanad, D., Joshi, M.S., Patil, R., et al.Synthesis and characterization of potential impurities in levothyroxineChem. Sci. Trans.5(4)1082-1089(2016)