An active metabolite of L-DOPA
货号:ajcx26656
CAS:7636-26-2
分子式:C10H13NO4
分子量：211.2
溶解度:Acetonitrile: Slightly soluble,Chloroform: Slightly soluble,DMF: Slightly soluble,DMSO: Slightly soluble,PBS (pH 7.2): Slightly soluble,Water: Slightly soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3-Methoxytyrosine is an active metabolite of L-DOPA .¹It is formed from L-DOPAviaO-methylation by catechol-O-methyltransferase (COMT). 3-Methoxytyrosine (10 and 100 µM) inhibits L-DOPA-induced neuroprotection in primary rat mesencephalic dopaminergic neurons.²

1.Miller, J.W., Shukitt-Hale, B., Villalobos-Molina, R., et al.Effect of ?-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in ratsClin. Neuropharmacol.20(1)55-66(1997) 2.Asanuma, M., and Miyazaki, I.3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of ?-DOPABMC Neurosci.17(1)52(2016)