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BigLEN(mouse)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BigLEN(mouse)图片
包装:1mg
规格:98%
市场价:1603元
分子量:1756.03

产品介绍
BigLEN (mouse) 是一种有效的、选择性的孤儿 G 蛋白偶联受体 171 (GPR171) 激动剂,Kd 为 ~0.5 nM。
货号:ajcx27518
CAS:501036-69-7
分子式:C78H130N24O22
分子量:1756.03
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.


Wardman et al (2011) ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake. PLoS One 6 e28152 PMID:22164236 |Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem.Neurosci. 10 1884 PMID:30726666