Dofetilide N-oxide (UK-116856) 是 Dofetilide 的代谢物。
货号:ajcx28290
CAS:144449-71-8
分子式:C19H27N3O6S2
分子量：457.6
溶解度:DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dofetilide N-oxide is a metabolite of the antiarrhythmic agent dofetilide .¹It prolongs intracellular action potential duration in isolated guinea pig papillary muscle, as a measure of antiarrhythmic activity, less potently than dofetilide.

1.Walker, D.K., Alabaster, C.T., Congrave, G.S., et al.Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo dataDrug Metab. Dispos.24(4)447-455(1996)