A potential impurity found in commercial preparations of lansoprazole
货号:ajcx28418
CAS:953787-54-7
分子式:C16H14F3N3O4S
分子量：401.4
溶解度:DMF: 1 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Lansoprazole sulfone N-oxide is a potential impurity found in commercial preparations of the proton pump inhibitor lansoprazole.¹It is a degradation product formed under oxidative conditions.²

1.Reddy, G.M., Mukkanti, K., Kumar, T.L., et al.Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drugSynth. Com.38(20)3477-3489(2008) 2.Shankar, G., Borkar, R.M., Suresh, U., et al.Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: In vitro toxicity evaluation of major degradation productsJ. Mass. Spectrom.52(7)459-471(2017)