Didesethylchloroquine(Bisdesethylchloroquine)是抗疟药Chloroquine的主要代谢物。Didesethylchloroquine是强效的心肌抑制剂。
货号:ajcx30518
CAS:4298-14-0
分子式:C14H18ClN3
分子量：263.77
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].

[1]. Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7. [2]. Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6.