Mito-apocynin(C2)，是一种基于三苯基膦(TPP)为靶点的口服活性线粒体化合物。Mito-apocynin(C2)由Apocynin部分与TPP+阳离子结合而合成。Mito-apocynin(C2)具有抗炎作用。
货号:ajcx31076
CAS:1254044-41-1
分子式:C28H27BrNO3P
分子量：536.4
溶解度:DMSO: 100 mg/mL (186.43 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1].

Mito-apocynin (C2) (3 mg/kg; p.o.; daily for 12 days) exhibits antineuroinflammatory effect[1]. Animal Model: MPTP mice model of Parkinson's Disease[1]

[1]. Zielonka J, et al. Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. Chem Rev. 2017 Aug 9;117(15):10043-10120.