您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > GPR30 agonist-1
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
GPR30 agonist-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GPR30 agonist-1图片
规格:98%
分子量:374.25
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
GPR30 agonist-1 是一种 G 蛋白偶联受体 30 (GPR30) 激动剂。GPR30 agonist-1 发挥血管舒张作用。
货号:ajcx32512
CAS:415919-74-3
分子式:C19H17BrFNO
分子量:374.25
溶解度:DMSO : 50 mg/mL (133.60 mM; ultrasonic and warming and heat to 80буC)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects[1].


GPR30 agonist-1 (compound 5408-0877) (1 nM-10 µM) induces a concentration-dependent relaxation in carotid arteries from both male and female rats. GPR30 agonist-1-induced relaxation is abolished by endothelium removal and abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 µM)[1].

参考文献:
[1]. Brad R S Broughton, et al. Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1055-61.