VU0080241 是一种代谢型谷氨酸受体 4 (mGluR4) 正变构调制剂 (PAM)，其 EC50 值为 4.6 µM。
货号:ajcx32574
CAS:393845-24-4
分子式:C19H23N5
分子量：321.42
溶解度:DMSO : 50 mg/mL (155.56 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 µM[1].

参考文献:
[1]. Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.