Sonlicromanol (KH176) hydrochloride 是 Trolox 的衍生物，是可透过血脑屏障的 ROS-redox 调节剂。Sonlicromanol (KH176) hydrochloride 可用于线粒体相关疾病研究。
货号:ajcx35210
CAS:2162149-24-6
分子式:C19H29ClN2O3
分子量：368.9
溶解度:DMSO : 170 mg/mL (460.83 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders[1].

Sonlicromanol (KH176) hydrochloride maintains microstructural coherence in the brain of Ndufs4-/- mice[1].

[1]. Ria de Haas, et al. Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease. Sci Rep. 2017 Sep 15;7(1):11733.