SG3199-Val-Ala-PAB 是 Tesirine 合成的中间体。Tesirine 是一种用于抗体偶联药物 (ADC) 的药物-linker 连接物，能用于多种癌症的研究。
货号:ajcx35624
CAS:1595275-61-8
分子式:C49H59N7O11
分子量：922.03
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SG3199-Val-Ala-PAB is an intermediate of Tesirine synthesis. Tesirine is a drug-linker conjugate for ADC which can be used for the research of several cancers[1].

SG3199-Val-Ala-PAB is an intermediate in in the synthesis of Tesirine, an antibody-drug conjugate pyrrolobenzodiazepine dimer payload[1].

[1]. Tiberghien AC, et, al. Design and Synthesis of Tesirine, a Clinical Antibody-Drug Conjugate Pyrrolobenzodiazepine Dimer Payload. ACS Med Chem Lett. 2016 May 24;7(11):983-987.