Amantadine (1-Adamantanamine) 是一种抗甲型流感 (influenza A) 病毒的抗病毒药物。Amantadine 阻断质子流通过 M2 离子通道 (M2 proton channel of influenza A)，从而阻止病毒 RNA 释放到感染细胞的细胞质中。Amantadine 抗帕金森病剂。
货号:ajcx36416
CAS:768-94-5
分子式:C10H17N
分子量：151.25
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent[1][2].

[1]. Suzuki H, et al. Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother. 2003;9(3):195-200.
[2]. Hubsher G, et al. Amantadine: the journey from fighting flu to treating Parkinson disease. Neurology. 2012;78(14):1096-1099.