Aspoxicillin 是一种广谱的抗菌剂，对分离的胸膜肺炎放线杆菌 68 菌株抑制作用的 MIC90 值<= 0.05 μg/ml。Aspoxicillin 在小鼠血清中的半衰期为 55 分钟。
货号:ajcx36552
CAS:63358-49-6
分子式:C21H27N5O7S
分子量：493.53
溶解度:H2O : 25 mg/mL (50.66 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of<= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes[1][2].

Aspoxicillin is a semisynthetic penicillin derivative[2]Aspoxicillin induces postantibiotic effects (PAEs) against Staphylococcus aureus Smith of 1.7 h in vitro[2].

Aspoxicillin induces PAEs against Staphylococcus aureus Smith of 5.2 h in vivo in a thigh infection model in neutropenic mice[2].

[1]. Yoshimura H, et al. Comparative in vitro activity of 16 antimicrobial agents against Actinobacillus pleuropneumoniae. Vet Res Commun. 2002 Jan;26(1):11-9.
[2]. Oshida T, et al. Activity of sub-minimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic effect against Staphylococcus aureus. J Antimicrob Chemother. 1990 Jul;26(1):29-38.