BMS-986278 是一种有效的 LPA1 拮抗剂，Kb 为 6.9 nM。
货号:ajcx36570
CAS:2170126-74-4
分子式:C22H31N5O5
分子量：445.51
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BMS-986278 is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist, with a human LPA1 Kb of 6.9 nM.

[1]. Cheng PTW, et al. Murphy BJ. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.