L-Isoleucine-15N 是一种 15N 标记的 L-Isoleucine。L-Isoleucine 是一种非极性疏水性氨基酸。L-Isoleucine 是一种必需氨基酸。
货号:ajcx37058
CAS:59935-30-7
分子式:C6H1315NO2
分子量：132.17
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Arkhipov SG, et al. New hydrophobic L-amino acid salts: maleates of L-leucine, L-isoleucine and L-norvaline. Acta Crystallogr C Struct Chem. 2015 Jul;71(Pt 7):584-92.