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Epsilon-(gamma-glutamyl)-lysine TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Epsilon-(gamma-glutamyl)-lysine TFA图片
规格:98%
分子量:389.32
包装与价格:
包装价格(元)
10mg电议
25mg电议

产品介绍
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA 是 N(6)-acyl-L-lysine 的衍生物。在一些疾病中 (如非糖尿病肾病,青光眼),组织转谷氨酰胺酶 (tTg) 使得 ECM 成分之间形成 Epsilon-(gamma-glutamyl)-lysine 键增加。
货号:ajcx37146
CAS:N/A
分子式:C13H22F3N3O7
分子量:389.32
溶解度:DMSO : 250 mg/mL (642.15 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].

[1]. Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45. [2]. A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.