Tivanisiran (SYL1001) 是一种 siRNA，可用于干眼症的研究。Tivanisiran 用于沉默TRPV1。
货号:ajcx38422
CAS:1848224-71-4
分子式:N/A
分子量：N/A
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1)[1].

In vitro transfection of tivanisiran was shown to produce a 50-60% decrease in TRPV1 mRNA levels[1][2].

[1]. Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to
[2]. Javier Moreno-MontaÑÉs, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.