CWHM-1008 是一种有效、可口服的抗疟疾剂，对药物不耐受型 Plasmodium falciparum 3D7 和耐受型 Dd2 的 EC50值分别为 46 和 21 nM。
货号:ajcx39308
CAS:2362539-97-5
分子式:C22H26F3N3O
分子量：405.46
溶解度:DMSO : 250 mg/mL (616.58 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CWHM-1008 is a potent and orally active antimalarial agent, with EC50 values of 46 and 21 nM against drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively[1].

[1]. Meyers MJ, et al. 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides. J Med Chem. 2019 Mar 22.