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Arterolane(OZ 277)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arterolane(OZ 277)图片
规格:98%
分子量:392.53
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
Arterolane是一种抗疟疾剂,对P.falciparumRo73和W2的IC50值均为1.1nM。
货号:ajcx12764
CAS:664338-39-0
分子式:C22H36N2O4
分子量:392.53
溶解度:DMSO : 100 mg/mL (254.76 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.

Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1].


[1]. Vennerstrom JL, et al. Identification of an antimalarial synthetic trioxolane drug development candidate. Nature. 2004 Aug 19;430(7002):900-4.