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Histone H3K27Me3(23-34)(human,mouse,rat,bovine)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Histone H3K27Me3(23-34)(human,mouse,rat,bovine)(trifluoroacetate salt)图片
包装:1mg
规格:98%
市场价:3392元
分子量:1156.3

产品介绍
Histone H3K27Me3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.
货号:ajcx18576
CAS:N/A
分子式:C49H89N17O15•XCF3COOH
分子量:1156.3
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Histone H3K27Me3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Trimethylation of histone H3 at lysine 27 is associated with gene silencing. It is involved in tumor progression through its regulation by enhancer of zeste homolog 2 (EZH2) and transcriptional repression of tumor suppressor genes. Levels of H3K27Me3 are reduced in 293 T-REx cells containing EEDR236T and SUZ12G610V mutations and in lymphoblastoid cells isolated from patients with Weaver syndrome, a rare overgrowth disorder characterized by EZH2, EED, or SUZ12 mutations, cancer susceptibility, and various distinctive physical features. Histone H3K27Me3 (23-34) has been used in AlphaLISA® assays to verify antibody specificity.