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PAR3(1-6)amide(mouse)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PAR3(1-6)amide(mouse)(trifluoroacetate salt)图片
规格:98%
分子量:576.6
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
PAR3 (1-6) amide is a synthetic hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse proteinase-activated receptor 3 (PAR3) and residues 38-43 of the full-length sequence.
货号:ajcx18830
CAS:N/A
分子式:C25H36N8O8•XCF3COOH
分子量:576.6
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

PAR3 (1-6) amide is a synthetic hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse proteinase-activated receptor 3 (PAR3) and residues 38-43 of the full-length sequence. PAR3 (1-6) amide activates PAR1 and PAR2, but not PAR3 or PAR4. It does not induce thrombin signaling in COS-7 cells expressing PAR3, PAR4, or both receptors at concentrations less than or equal to 500 µM, however, it does activate PAR1 and PAR2 in a cross-desensitization assay in Jurkat T cells when used at concentrations of 500 and 1,000 µM. PAR3 (1-6) increases calcium levels in Kirsten virus-transformed rat kidney (KNRK) cells expressing rat or human PAR2, with a higher potency for rat PAR2.