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(-)-Hyoscyamine-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-Hyoscyamine-d3图片
包装:5mg
规格:98%
市场价:10060元
分子量:292.4

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx20810
CAS:N/A
分子式:C17H20D3NO3
分子量:292.4
溶解度:Chloroform: 50 mg/ml,Ethanol: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

(-)-Hyoscyamine-d3is intended for use as an internal standard for the quantification of (-)-hyoscyamine by GC- or LC-MS. (-)-Hyoscyamine is a tropane alkaloid, a muscarinic receptor antagonist, and an isomer of atropine .1,2(-)-Hyoscyamine inhibits the arterial depressor response induced by the muscarinic agonist methacholine in dogs.1It is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation when administered at doses of 0.5 and 1 mg/kg. (-)-Hyoscyamine induces convulsions in and is toxic to mice (LD50= 95 mg/kg).2


1.Domino, E.F., and Hudson, R.D.Observations on the pharmacological actions of the isomers of atropineJ. Pharmacol. Exp. Ther.127(4)305-312(1959) 2.Authority, E.F.S.Scientific Opinion on Tropane alkaloids in food and feed EFSA Panel on contaminants in the food chain (CONTAM)EFSA J.11(10)3386(2013)