A bacterial metabolite
货号:ajcx23692
CAS:98474-21-6
分子式:C43H56O17
分子量：844.9
溶解度:Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Urdamycin A is a bacterial metabolite originally isolated fromS. fradiaethat has antibacterial and anticancer activities.^1,2It is active against a variety of Gram-positive and Gram-negative bacteria, includingB. subtilisand strains ofArthrobacterandStreptomyces, but not the fungusS. cerevisiae, in a disc assay when used at a concentration of 1 mg/ml.²Urdamycin A is cytotoxic to L1210 and HT-29, but not A549, cancer cells (IC₅₀s = 7.5, 5, and >10 µg/ml, respectively).¹

1.Henkel, T., Ciesiolka, T., Rohr, J., et al.Urdamycins, new angucycline antibiotics from Streptomyces fradiae. V. Derivatives of urdamycin AJ. Antibiot. (Tokyo)42(2)299-311(1989) 2.Drautz, H., ZÄhner, H., Rohr, J., et al.Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I. Isolation, characterization and biological propertiesJ. Antibiot. (Tokyo)39(12)1657-1669(1986)