Trifluoperazine N-Glucuronide (UGT1A4) 作为人类 UGT1A 亚型之一，在肝脏中表达。
货号:ajcx25402
CAS:165602-90-4
分子式:C27H32F3N3O6S
分子量：583.6
溶解度:Methanol: soluble,Water: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Trifluoperazine N-glucuronide is a metabolite of the antipsychotic agent trifluoperazine .^1,2It is formed from trifluoperazine by the UDP-glucuronosyltransferase (UGT) isoform UGT1A4.²

1.Luo, H., Hawes, E.M., McKay, G., et al.N(+)-glucuronidation of aliphatic tertiary amines in human: antidepressant versus antipsychotic drugsXenobiotica25(3)291-301(1995) 2.Fujiwara, R., Nakajima, M., Yamanaka, H., et al.Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activitiesDrug Metab. Dispos.35(10)1781-1787(2007)