包装: | 1mg |
规格: | 98% |
市场价: | 6571元 |
分子量: | 568.5 |
Background:
SN-38 Glucuronide is a phase II metabolite of irinotecan .1It is formedviaglucuronidation of the irinotecan phase I metabolite SN-38 by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1.
1.Hirose, K., Kozu, C., Yamashita, K., et al.Correlation between plasma concentration ratios of SN-38 glucuronide and SN-38 and neutropenia induction in patients with colorectal cancer and wild-type UGT1A1 geneOncol. Lett.3(3)694-698(2012)