| 规格: | 98% |
| 分子量: | 370.21 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 10mg | 电议 |
Background:
Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 μM respectively) and displays > 3-fold selectivity over FGFR-1. Orally active in vivo.
Hennequin et al (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J.Med.Chem. 42 5369 PMID:10639280
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